Nesting & denesting of prefilled syringes (PFS) in Tubs

Nesting & denesting of prefilled syringes (PFS) in Tubs

Performance and Reliability Pre-filled syringe nesting and denesting machines ensure precise and reliable packaging in nests, guaranteeing performance, safety, and cost-effectiveness. With their unique gripper and optimized robot trajectories, these machines perform handling operations while minimizing cycle time.

Automated Process Tubs are automatically conveyed to the nesting or denesting stations via a dedicated conveyor. The robot then retrieves the syringes and places them precisely onto a conveyor (denesting) or into the nest (nesting). Specific solutions ensure the absence of glass-to-glass or glass-to-metal contact between products. The achieved precision guarantees the integrity of the syringes throughout the process.

Multiple Speed Options The various solutions developed by CILYX allow operation at different speeds, from 150 cycles per minute to 1000 cycles per minute (9,000 to 60,000 syringes per hour). These machines offer exceptional productivity. The compact design of the nesting and denesting machines allows for easy integration into existing production lines.

Benefits The denesters and renesters meet the stringent requirements of the pharmaceutical industry in terms of reliability, robustness, and compactness. Their seamless integration into new or existing production lines increases productivity while ensuring operator safety.

Compliance and Certification CE-certified, these machines meet all the requirements of cGMP and GAMP5 good manufacturing practices, ensuring full compliance with industry quality and safety standards.

Advantages

  • Increased Precision: With a unique gripper and optimized robot trajectories, these machines ensure precise placement of syringes, minimizing errors and maintaining product integrity.
  • Operational Efficiency: Handling operations are performed with minimal cycle time, enhancing the speed and efficiency of the packaging process.
  • Full Automation: Tubs are automatically conveyed to the nest or denest stations via a dedicated conveyor, reducing the need for manual intervention and increasing productivity.
  • Product integrity: Specific solutions prevent glass-to-glass or glass-to-metal contact between products, ensuring safe handling without the risk of contamination and preserving syringe integrity.
  • Variable Speed Flexibility: The machines offer variable speeds, ranging from 150 to 1000 cycles per minute (equivalent to 9,000 to 60,000 syringes per hour), allowing for diverse production needs and adaptability to varying volume demands.
  • Compactness and Easy Integration: The compact design of the machines allows for easy integration into existing production lines, optimizing space and enabling seamless installation without major modifications.
  • High Productivity: With exceptional performance, these machines enable high levels of productivity, improving the overall efficiency of the production line.
  • Compliance and Certification: CE-certified and compliant with cGMP and GAMP5 good manufacturing practices, these machines meet the stringent quality and safety standards of the pharmaceutical industry.

Options

Accumulation table (buffer)

The accumulation tables placed at the machine’s entry (denesting) or exit (nesting) increase the machine’s autonomy and reduce operator intervention time.

Palletizing or depalletizing systems.

The palletizing or depalletizing systems placed at the machine’s entry (denesting) or exit (nesting) increase the machine’s autonomy and reduce operator intervention time.

Inlet or outlet conveyors

The conveyors connect upstream or downstream machines to ensure the continuous flow of syringes along the line. The conveyors can also serve as a buffer between two machines.

Tubs or nests automatic storage

The tub and nest magazines placed at the machine’s entry (nesting) or exit (denesting) increase the machine’s autonomy and reduce operator intervention time.

Syringes counter

Thanks to a vision system, syringe counting ensures the proper filling of nests at the output of the nesting machine.

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Depalletization & palletization

Handling of tubs of syringes or cartridges and trays of vials to improve productivity
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Loading & unloading of vials in Akylux Trays

Loading and unloading of vials in trays or in Akylux trays.
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Conveyors

Conveyors for prefilled syringes (PFS) using polycords or contact less. Conveyors for vials.
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Buffers

Production line buffering systems for syringes and vials
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Labelling

Labelling of pre-filled syringes, vials or other primary containers
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Serialization of glass containers based on the NAGINELS technology

Serialization of pharmaceutical glass containers (Pre-filled syringes and vials).
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